Topic 4: Epidemiology, Biostatistics, Genetics, and Genomics
Topic 4: Epidemiology, Biostatistics, Genetics, and Genomics
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Objectives:
- Describe the role of epidemiology in researching and addressing population health
- Discuss the value of biostatistics in population health
- Connect ecological, global, and social determinants of health and principles of genetics, genomics, and epidemiology to translational
Topic 4: Epidemiology, Biostatistics, Genetics, and Genomics Study Materials
Population Health: Creating a Culture of Wellness
Description:
Read Chapters 2-4 in Population Health: Creating a Culture of Wellness.
Advanced Nursing Research: From Theory to Practice
Description:
Read Chapter 7 in Advanced Nursing Research: From Theory to Practice.
The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact
Description:
Read “The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact,” by Khoury, Gwinn, and Ioannidis, from American Journal of Epidemiology(2010).
Beyond Base Pairs to Bedside: a Population Perspective on How Genomics Can Improve Health
Description:
Read “Beyond Base Pairs to Bedside: A Population Perspective on How Genomics Can Improve Health,” by Khoury, Gwinn, Bowen, and Dotson, fromAmerican Journal of Public Health (2012).
Translational Research in Genomics of Alzheimer’s Disease: A Review of Current Practice and Future Perspectives
Description:
Read “Translational Research in Genomics of Alzheimer’s Disease: A Review of Current Practice and Future Perspectives,” by Mihaescu, Detmar, Cornel, van der Flier, Heutink, Hol, Rikkert, van Duijn, and Janssens, from Journal of Alzheimer’s Disease (2010).
Personalizing Health Care: Feasibility and Future Implications
Description:
Read “Personalizing Health Care: Feasibility and Future Implications,” by Godman, Finlayson, Cheema,
Zebedin-Brandl, Gutiérrez-Ibarluzea, Jones, Malmström, Asola, Baumgärtel, Bennie, Bishop, Bucsics, Campbell, Diogene, Ferrario, Fürst, Garuoliene, Gomes, Harris, and Haycox, from BMC Medicine (2013).
Epigenetics and Understanding the Impact of Social Determinants of Health
Description:
Read “Epigenetics and Understanding the Impact of Social Determinants of Health,” by Notterman and Mitchell, from
Pediatric Clinics of North America(2015).
United States Census Bureau
Description:
Tasks
Topic 5: Evidence for Improving Safety and Quality and Barriers to Translation
Description
Objectives:
- Explain how translational r can be used for safety and quality improvement initiatives related to improving population
- Discuss common barriers for translating research into
Study Materials
Tasks
Topic 6: Quality Improvement Initiatives and Clinical Prevention Interventions
Description
Objectives:
- Evaluate quality improvement initiatives related to improving population health
- Evaluate clinical prevention interventions that promote health and wellness for
Study Materials
Tasks
Benchmark – Part B: Literature Review
Description:
In Part A, you described the population and quality initiative related to your PICOT (Population/P roblem, Intervention, Comparison, Outcome, and Time to achieve the outcome) statement. In this assignment, you will formalize your PICOT and research process.
Use the GCU Library to perform a search for peer-reviewed research articles. Find five peer-reviewed primary source translational research articles.
In a paper of 1,250-1,500 words, synthesize the research into a literature review. The literature review should provide an overview for the reader that illustrates the research related to your particular PICOT. Include the following:
- Introduction: Describe the clinical issue or problem you are
- Methods: Describe the criteria you used in choosing your articles
- Synthesize the Literature: Part A: Discuss the main components of each article (subjects, methods, key findings) and provide rationale for how this supports your PICOT; Part B: Compare and contrast the articles: Discuss limitations, controversies, and similarities/differences of the
- Areas of Further Study: Analyze the evidence presented in your articles to identify what is known, unknown, and requires further
Topic 4: Epidemiology, Biostatistics, Genetics, and Genomics
You are required to cite five to 10 sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.
Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.
This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.
You are required to submit this assignment to LopesWrite. Please refer to the directions in the Student Success Center.
NUR-550 – Translational Research and Population Health Management
Topic 6 DQ 1
Description:
Identify a quality improvement initiative that relates to improving population health outcomes for a population with which you are familiar. Have these initiatives been successful? Why or why not?
Topic 6 DQ 2
Description:
Topic 7: Policies Affecting Practice and State of Health Care Delivery
Description
Objectives:
- Identify major policy issues affecting the state of health care delivery and population health
- Analyze the components of effective populationbased health
- Discuss the impact of population health policies and initiatives on advanced nursing
Study Materials
Tasks
Objectives: Description
Topic 8: Using Research to Support Health Policy, Advocacy and Policy Development
- Discuss the role of translational research in advancing equitable access to health care and prevention services and policies based on population
- Evaluate the role of the advanced practice nurse in advocating for equitable population health services and
Study Materials
Tasks
Benchmark – Population Health Policy Analysis
Description:
Select a current or proposed health care policy that is designed to improve a specific population’s access to quality, cost-effective health care. In a of 1,000-1,250 words, include the following:
- Explain the policy and how it is designed to improve cost-effectiveness and health care equity for the population. Is the policy financially sound? Why or why not? How does the policy account for any relevant ethical, legal, and political factors and the nursing perceptive one must consider when implementing it?
- To what state, federal, global health policies or goals is this particular policy related? How well do you think the policy is designed to achieve those goals?
- Finally, discuss the advocacy strategies you would employ on behalf of your population to ensure they have access to the benefits of the Explain, from a Christian perspective, the professional and moral obligation of advanced registered nurse to advocate for and promote health and prevent disease among diverse populations.
You are required to cite five to 10 sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.
Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.
This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.
You are required to submit this assignment to LopesWrite. Please refer to the directions in the Student Success Center.
NUR-550 – Translational Research and Population Health Management
Topic 8 DQ 1
Description:
Define how translational research plays a role in influencing policy? Provide an example of a local health care policy that has been recently enacted and or is awaiting legislative passage that has been influenced by research.
Topic 4: Epidemiology, Biostatistics, Genetics, and Genomics
Topic 8 DQ 2
Description:
As an advanced registered nurse, what will your role be in advocating for equitable population health services and policies? Do you anticipate any challenges or barriers to “population advocacy”?
| Letter Grade | GPA Value | Minimum (%) | Maximum (%) |
| A | 4.0 | 97.0 | 100.0 |
| A- | 3.7 | 93.0 | 96.99 |
| B+ | 3.3 | 89.0 | 92.99 |
| B | 3.0 | 85.0 | 88.99 |
| B- | 2.7 | 81.0 | 84.99 |
| C+ | 2.3 | 78.0 | 80.99 |
| C | 2.0 | 76.0 | 77.99 |
| F | 0.0 | 1.0 | 75.99 |
| I | 0.0 | 0.5 | 0.99 |
| W | 0.0 | 0.0 | 0.49 |
Grade Scale
Final Grade Column
Grade Categories
| Assignments (%) | Points | Percentile |
| Translational Research Graphic Organizer | 100.0 | — |
| Benchmark – Population Health Policy Analysis | 160.0 | — |
| Benchmark – Part A: Population Health Research and PICOT Statement |
250.0 |
— |
| Benchmark – Part B: Literature Review | 250.0 | — |
| Discussion Question (%) | Points | Percentile |
| Topic 4 DQ 2 | 5.0 | — |
| Topic 2 DQ 2 | 5.0 | — |
| Topic 5 DQ 2 | 5.0 | — |
| Topic 7 DQ 1 | 5.0 | — |
| Topic 3 DQ 2 | 5.0 | — |
| Topic 5 DQ 1 | 5.0 | — |
| Topic 8 DQ 1 | 5.0 | — |
| Topic 7 DQ 2 | 5.0 | — |
| Topic 6 DQ 2 | 5.0 | — |
| Topic 1 DQ 1 | 5.0 | — |
| Topic 1 DQ 2 | 5.0 | — |
| Topic 4 DQ 1 | 5.0 | — |
NUR-550 – Translational Research and Population Health Management
| Topic 3 DQ 1 | 5.0 | — |
| Topic 6 DQ 1 | 5.0 | — |
| Topic 8 DQ 2 | 5.0 | — |
| Topic 2 DQ 1 | 5.0 | — |
| Participation (%) Points Percentile |
| 20.0 — |
| Participation (%) Points Percentile |
| 20.0 — |
| Participation (%) Points Percentile |
| 20.0 — |
| Participation (%) Points Percentile |
| 20.0 — |
| Participation (%) Points Percentile |
| 20.0 — |
NUR-550 – Translational Research and Population Health Management
| Participation (%) Points Percentile |
| 20.0 — |
| Participation (%) Points Percentile |
| 20.0 — |
| Participation (%) Points Percentile |
| 20.0 — |
| Class Effective Start: Apr 11, 2019 |
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Topic 4: Epidemiology, Biostatistics, Genetics, and Genomics
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